Electrophysiological mechanisms of vandetanib-induced cardiotoxicity: Comparison of action potential...
Electrophysiological mechanisms of vandetanib-induced cardiotoxicity: Comparison of action potentials in rabbit Purkinje fibers and pluripotent stem cell-derived cardiomyocytes
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Vandetanib, a multi-kinase inhibitor used for the treatment of various cancers, has been reported to induce several adverse cardiac effects. However, the underlying mechanisms of vandetanib-induced cardiotoxicity are unclear. This study aimed to investigate the mechanism of vandetanib-induced cardiotoxicity using intracellular electrophysiological...
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Full title
Electrophysiological mechanisms of vandetanib-induced cardiotoxicity: Comparison of action potentials in rabbit Purkinje fibers and pluripotent stem cell-derived cardiomyocytes
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TN_cdi_plos_journals_2023410658
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2023410658
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0195577
