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Relatively slow stochastic gene-state switching in the presence of positive feedback significantly b...

Relatively slow stochastic gene-state switching in the presence of positive feedback significantly b...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2025710431

Relatively slow stochastic gene-state switching in the presence of positive feedback significantly broadens the region of bimodality through stabilizing the uninduced phenotypic state

About this item

Full title

Relatively slow stochastic gene-state switching in the presence of positive feedback significantly broadens the region of bimodality through stabilizing the uninduced phenotypic state

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2018-03, Vol.14 (3), p.e1006051

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

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Scope and Contents

Contents

Within an isogenic population, even in the same extracellular environment, individual cells can exhibit various phenotypic states. The exact role of stochastic gene-state switching regulating the transition among these phenotypic states in a single cell is not fully understood, especially in the presence of positive feedback. Recent high-precision...

Alternative Titles

Full title

Relatively slow stochastic gene-state switching in the presence of positive feedback significantly broadens the region of bimodality through stabilizing the uninduced phenotypic state

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2025710431

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2025710431

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1006051

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