Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Rol...
Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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During hemolysis, hemoglobin and heme released from red blood cells promote oxidative stress, inflammation and thrombosis. Plasma haptoglobin and hemopexin scavenge free hemoglobin and heme, respectively, but can be depleted in hemolytic states. Haptoglobin and hemopexin supplementation protect tissues, including the vasculature, liver and kidneys....
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Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction
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TN_cdi_plos_journals_2030876660
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2030876660
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0196455
