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Divergent antioxidant capacity of human islet cell subsets: A potential cause of beta-cell vulnerabi...

Divergent antioxidant capacity of human islet cell subsets: A potential cause of beta-cell vulnerabi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2034346995

Divergent antioxidant capacity of human islet cell subsets: A potential cause of beta-cell vulnerability in diabetes and islet transplantation

About this item

Full title

Divergent antioxidant capacity of human islet cell subsets: A potential cause of beta-cell vulnerability in diabetes and islet transplantation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-05, Vol.13 (5), p.e0196570-e0196570

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Type 1 and Type 2 diabetes mellitus (T1DM and T2DM) are caused by beta(β)-cell loss and functional impairment. Identification of mechanisms of β-cell death and therapeutic interventions to enhance β-cell survival are essential for prevention and treatment of diabetes. Oxidative stress is a common feature of both T1DM and T2DM; elevated biomarkers o...

Alternative Titles

Full title

Divergent antioxidant capacity of human islet cell subsets: A potential cause of beta-cell vulnerability in diabetes and islet transplantation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2034346995

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2034346995

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0196570

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