Improving Acetate Tolerance of Escherichia coli by Rewiring Its Global Regulator cAMP Receptor Prote...
Improving Acetate Tolerance of Escherichia coli by Rewiring Its Global Regulator cAMP Receptor Protein (CRP)
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The presence of acetate exceeding 5 g/L is a major concern during E. coli fermentation due to its inhibitory effect on cell growth, thereby limiting high-density cell culture and recombinant protein production. Hence, engineered E. coli strains with enhanced acetate tolerance would be valuable for these bioprocesses. In this work, the acetate toler...
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Improving Acetate Tolerance of Escherichia coli by Rewiring Its Global Regulator cAMP Receptor Protein (CRP)
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TN_cdi_plos_journals_2037235139
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2037235139
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0077422