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Improving Acetate Tolerance of Escherichia coli by Rewiring Its Global Regulator cAMP Receptor Prote...

Improving Acetate Tolerance of Escherichia coli by Rewiring Its Global Regulator cAMP Receptor Prote...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2037235139

Improving Acetate Tolerance of Escherichia coli by Rewiring Its Global Regulator cAMP Receptor Protein (CRP)

About this item

Full title

Improving Acetate Tolerance of Escherichia coli by Rewiring Its Global Regulator cAMP Receptor Protein (CRP)

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-10, Vol.8 (10), p.e77422

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The presence of acetate exceeding 5 g/L is a major concern during E. coli fermentation due to its inhibitory effect on cell growth, thereby limiting high-density cell culture and recombinant protein production. Hence, engineered E. coli strains with enhanced acetate tolerance would be valuable for these bioprocesses. In this work, the acetate toler...

Alternative Titles

Full title

Improving Acetate Tolerance of Escherichia coli by Rewiring Its Global Regulator cAMP Receptor Protein (CRP)

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2037235139

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2037235139

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0077422

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