Gaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Gba1 Mutant Mouse M...
Gaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Gba1 Mutant Mouse Model Treated with Velaglucerase alfa or Imiglucerase
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Gaucher disease type 1, an inherited lysosomal storage disorder, is caused by mutations in GBA1 leading to defective glucocerebrosidase (GCase) function and consequent excess accumulation of glucosylceramide/glucosylsphingosine in visceral organs. Enzyme replacement therapy (ERT) with the biosimilars, imiglucerase (imig) or velaglucerase alfa (vela...
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Full title
Gaucher Disease: Transcriptome Analyses Using Microarray or mRNA Sequencing in a Gba1 Mutant Mouse Model Treated with Velaglucerase alfa or Imiglucerase
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TN_cdi_plos_journals_2037237415
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2037237415
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0074912
