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Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experime...

Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experime...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2039652376

Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experimental Chagas Disease

About this item

Full title

Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experimental Chagas Disease

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-06, Vol.10 (6), p.e0128707

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The nitroheterocyclic drugs nifurtimox and benznidazole are first-line drugs available to treat Chagas disease; however, they have limitations, including long treatment courses and toxicity. Strategies to overcome these limitations include the identification of new drugs with specific target profiles, re-dosing regimens for the current drugs, drug...

Alternative Titles

Full title

Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experimental Chagas Disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2039652376

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2039652376

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0128707

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