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Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implica...

Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implica...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2039765167

Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy

About this item

Full title

Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2018-04, Vol.14 (4), p.e1006956

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Autologous transplantation and engraftment of HIV-resistant cells in sufficient numbers should recapitulate the functional cure of the Berlin Patient, with applicability to a greater number of infected individuals and with a superior safety profile. A robust preclinical model of suppressed HIV infection is critical in order to test such gene therap...

Alternative Titles

Full title

Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2039765167

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2039765167

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1006956

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