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Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure...

Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2039772054

Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure of vivax malaria

About this item

Full title

Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure of vivax malaria

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2018-04, Vol.12 (4), p.e0006440-e0006440

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The 8-aminoquinoline antimalarials, the only drugs which prevent relapse of vivax and ovale malaria (radical cure), cause dose-dependent oxidant haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Patients with <30% and <70% of normal G6PD activity are not given standard regimens of primaquine and tafenoquine, respec...

Alternative Titles

Full title

Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure of vivax malaria

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2039772054

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2039772054

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0006440

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