Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure...
Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure of vivax malaria
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The 8-aminoquinoline antimalarials, the only drugs which prevent relapse of vivax and ovale malaria (radical cure), cause dose-dependent oxidant haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Patients with <30% and <70% of normal G6PD activity are not given standard regimens of primaquine and tafenoquine, respec...
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Full title
Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure of vivax malaria
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TN_cdi_plos_journals_2039772054
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2039772054
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ISSN
1935-2735,1935-2727
E-ISSN
1935-2735
DOI
10.1371/journal.pntd.0006440