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Differential Effects of Dabigatran and Warfarin on Bone Volume and Structure in Rats with Normal Ren...

Differential Effects of Dabigatran and Warfarin on Bone Volume and Structure in Rats with Normal Ren...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2044550026

Differential Effects of Dabigatran and Warfarin on Bone Volume and Structure in Rats with Normal Renal Function

About this item

Full title

Differential Effects of Dabigatran and Warfarin on Bone Volume and Structure in Rats with Normal Renal Function

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-08, Vol.10 (8), p.e0133847-e0133847

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Warfarin, a widely used anticoagulant, is a vitamin K antagonist impairing the activity of vitamin K-dependent Bone Gla Protein (BGP or Osteocalcin) and Matrix Gla Protein (MGP). Because dabigatran, a new anticoagulant, has no effect on vitamin K metabolism, the aim of this study was to compare the impact of warfarin and dabigatran administration o...

Alternative Titles

Full title

Differential Effects of Dabigatran and Warfarin on Bone Volume and Structure in Rats with Normal Renal Function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2044550026

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2044550026

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0133847

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