Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation i...
Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Drug-related sinusoidal dilatation (SD) is a common form of hepatotoxicity associated with oxaliplatin-based chemotherapy used prior to resection of colorectal liver metastases (CRLM). Recently, hepatic SD has also been associated with anti-delta like 4 (DLL4) cancer therapies targeting the NOTCH pathway. To investigate the hypothesis that NOTCH si...
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Full title
Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer
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TN_cdi_plos_journals_2051644806
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2051644806
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0198099
