Degenerate Pax2 and Senseless binding motifs improve detection of low-affinity sites required for en...
Degenerate Pax2 and Senseless binding motifs improve detection of low-affinity sites required for enhancer specificity
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Cells use thousands of regulatory sequences to recruit transcription factors (TFs) and produce specific transcriptional outcomes. Since TFs bind degenerate DNA sequences, discriminating functional TF binding sites (TFBSs) from background sequences represents a significant challenge. Here, we show that a Drosophila regulatory element that activates...
Alternative Titles
Full title
Degenerate Pax2 and Senseless binding motifs improve detection of low-affinity sites required for enhancer specificity
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2056433579
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2056433579
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1007289
