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Corticosteroid inhibits differentiation of palmar fibromatosis-derived stem cells (FSCs) through dow...

Corticosteroid inhibits differentiation of palmar fibromatosis-derived stem cells (FSCs) through dow...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2059528324

Corticosteroid inhibits differentiation of palmar fibromatosis-derived stem cells (FSCs) through downregulation of transforming growth factor-β1 (TGF-β1)

About this item

Full title

Corticosteroid inhibits differentiation of palmar fibromatosis-derived stem cells (FSCs) through downregulation of transforming growth factor-β1 (TGF-β1)

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-06, Vol.13 (6), p.e0198326-e0198326

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Treatment for musculoskeletal fibromatosis remains challenging. Surgical excision for fibromatosis is the standard therapy but recurrence remains high. Corticosteroids, an anti-fibrogenic compound, have been used to treat early stage palmar fibromatosis, but the mechanism is unknown. We investigated the inhibitory mechanism effect of corticosteroid...

Alternative Titles

Full title

Corticosteroid inhibits differentiation of palmar fibromatosis-derived stem cells (FSCs) through downregulation of transforming growth factor-β1 (TGF-β1)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2059528324

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2059528324

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0198326

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