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Mitochondrial Ca2+ flux modulates spontaneous electrical activity in ventricular cardiomyocytes

Mitochondrial Ca2+ flux modulates spontaneous electrical activity in ventricular cardiomyocytes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2068891870

Mitochondrial Ca2+ flux modulates spontaneous electrical activity in ventricular cardiomyocytes

About this item

Full title

Mitochondrial Ca2+ flux modulates spontaneous electrical activity in ventricular cardiomyocytes

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-07, Vol.13 (7), p.e0200448-e0200448

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Ca2+ release from sarcoplasmic reticulum (SR) is known to contribute to automaticity via the cytoplasmic Na+-Ca2+ exchanger (NCX). Mitochondria participate in Ca2+ cycling. We studied the role of mitochondrial Ca2+ flux in ventricular spontaneous electrical activity.
Spontaneously contracting mouse embryonic stem cells (ESC)-derived ventricular...

Alternative Titles

Full title

Mitochondrial Ca2+ flux modulates spontaneous electrical activity in ventricular cardiomyocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2068891870

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2068891870

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0200448

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