CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiova...
CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine
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Author / Creator
Ale-Agha, Niloofar , Goy, Christine , Jakobs, Philipp , Spyridopoulos, Ioakim , Gonnissen, Stefanie , Dyballa-Rukes, Nadine , Aufenvenne, Karin , von Ameln, Florian , Zurek, Mark , Spannbrucker, Tim , Eckermann, Olaf , Jakob, Sascha , Gorressen, Simone , Abrams, Marcel , Grandoch, Maria , Fischer, Jens W , Köhrer, Karl , Deenen, René , Unfried, Klaus , Altschmied, Joachim and Haendeler, Judith
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
We show that the cyclin-dependent kinase inhibitor 1B (CDKN1B)/p27, previously known as a cell cycle inhibitor, is also localized within mitochondria. The migratory capacity of endothelial cells, which need intact mitochondria, is completely dependent on mitochondrial p27. Mitochondrial p27 improves mitochondrial membrane potential, increases adeno...
Alternative Titles
Full title
CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine
Authors, Artists and Contributors
Author / Creator
Goy, Christine
Jakobs, Philipp
Spyridopoulos, Ioakim
Gonnissen, Stefanie
Dyballa-Rukes, Nadine
Aufenvenne, Karin
von Ameln, Florian
Zurek, Mark
Spannbrucker, Tim
Eckermann, Olaf
Jakob, Sascha
Gorressen, Simone
Abrams, Marcel
Grandoch, Maria
Fischer, Jens W
Köhrer, Karl
Deenen, René
Unfried, Klaus
Altschmied, Joachim
Haendeler, Judith
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2070854106
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2070854106
Other Identifiers
ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.2004408
