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Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency

Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2070862025

Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency

About this item

Full title

Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2018-06, Vol.14 (6), p.e1007476-e1007476

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In response to iron deficiency, the budding yeast Saccharomyces cerevisiae undergoes a metabolic remodeling in order to optimize iron utilization. The tandem zinc finger (TZF)-containing protein Cth2 plays a critical role in this adaptation by binding and promoting the degradation of multiple mRNAs that contain AU-rich elements (AREs). Here, we dem...

Alternative Titles

Full title

Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2070862025

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2070862025

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1007476

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