Humanized anti-Sialyl-Tn antibodies for the treatment of ovarian carcinoma
Humanized anti-Sialyl-Tn antibodies for the treatment of ovarian carcinoma
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The expression of Sialyl-Tn (STn) in tumors is associated with metastatic disease, poor prognosis, and reduced overall survival. STn is expressed on ovarian cancer biomarkers including CA-125 (MUC16) and MUC1, and elevated serum levels of STn in ovarian cancer patients correlate with lower five-year survival rates. In the current study, we humanize...
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Full title
Humanized anti-Sialyl-Tn antibodies for the treatment of ovarian carcinoma
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TN_cdi_plos_journals_2077456098
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2077456098
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0201314
