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Study of purinosome assembly in cell-based model systems with de novo purine synthesis and salvage p...

Study of purinosome assembly in cell-based model systems with de novo purine synthesis and salvage p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2079927862

Study of purinosome assembly in cell-based model systems with de novo purine synthesis and salvage pathway deficiencies

About this item

Full title

Study of purinosome assembly in cell-based model systems with de novo purine synthesis and salvage pathway deficiencies

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-07, Vol.13 (7), p.e0201432-e0201432

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The enzymes involved in de novo purine synthesis (DNPS), one of the basic processes in eukaryotic cells, transiently and reversibly form a dynamic multienzyme complex called the purinosome in the cytoplasm. The purinosome has been observed in a broad spectrum of cells, but some studies claim that it is an artefact of the constructs used for visuali...

Alternative Titles

Full title

Study of purinosome assembly in cell-based model systems with de novo purine synthesis and salvage pathway deficiencies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2079927862

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2079927862

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0201432

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