The role of AKT and FOXO3 in preventing ovarian toxicity induced by cyclophosphamide
The role of AKT and FOXO3 in preventing ovarian toxicity induced by cyclophosphamide
About this item
Full title
Author / Creator
Zhang, Bao-Fang , Hu, YaXin , Liu, Xinyan , Cheng, Zhuo , Lei, Yu , Liu, YongMei , Zhao, Xueke , Mu, Mao , Yu, Lei and Cheng, Ming-Liang
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Cyclophosphamide (CTX) has immunosuppressive effects and has been wildly used as one anti-cancer drug in clinical. Significant toxicity has been noticed particularly in the reproductive system. CTX promotes the maturation of ovarian follicles, decreases follicular reserve, and ultimately lead to ovarian failure or even premature ovarian failure (PO...
Alternative Titles
Full title
The role of AKT and FOXO3 in preventing ovarian toxicity induced by cyclophosphamide
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2082111062
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2082111062
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0201136
