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Distinct amino acid motifs carrying multiple positive charges regulate membrane targeting of dysferl...

Distinct amino acid motifs carrying multiple positive charges regulate membrane targeting of dysferl...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2086258652

Distinct amino acid motifs carrying multiple positive charges regulate membrane targeting of dysferlin and MG53

About this item

Full title

Distinct amino acid motifs carrying multiple positive charges regulate membrane targeting of dysferlin and MG53

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-08, Vol.13 (8), p.e0202052-e0202052

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Dysferlin (Dysf) and mitsugumin53 (MG53) are two key proteins involved in membrane repair of muscle cells which are efficiently recruited to the sarcolemma upon lesioning. Plasma membrane localization and recruitment of a Dysf fragment to membrane lesions in zebrafish myofibers relies on the presence of a short, polybasic amino acid motif, WRRFK. H...

Alternative Titles

Full title

Distinct amino acid motifs carrying multiple positive charges regulate membrane targeting of dysferlin and MG53

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2086258652

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2086258652

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0202052

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