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Hypoxic cardiac fibroblasts from failing human hearts decrease cardiomyocyte beating frequency in an...

Hypoxic cardiac fibroblasts from failing human hearts decrease cardiomyocyte beating frequency in an...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2092586409

Hypoxic cardiac fibroblasts from failing human hearts decrease cardiomyocyte beating frequency in an ALOX15 dependent manner

About this item

Full title

Hypoxic cardiac fibroblasts from failing human hearts decrease cardiomyocyte beating frequency in an ALOX15 dependent manner

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-08, Vol.13 (8), p.e0202693-e0202693

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

A common denominator for patients with heart failure is the correlation between elevated serum levels of proinflammatory cytokines and adverse clinical outcomes. Furthermore, lipoxygenase-induced inflammation is reportedly involved in the pathology of heart failure. Cardiac fibroblasts, which are abundant in cardiac tissue, are known to be activate...

Alternative Titles

Full title

Hypoxic cardiac fibroblasts from failing human hearts decrease cardiomyocyte beating frequency in an ALOX15 dependent manner

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2092586409

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2092586409

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0202693

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