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Grxcr2 is required for stereocilia morphogenesis in the cochlea

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Grxcr2 is required for stereocilia morphogenesis in the cochlea

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2096655350

Grxcr2 is required for stereocilia morphogenesis in the cochlea

About this item

Full title

Grxcr2 is required for stereocilia morphogenesis in the cochlea

Author / Creator

Avenarius, Matthew R , Jung, Jae-Yun , Askew, Charles , Jones, Sherri M , Hunker, Kristina L , Azaiez, Hela , Rehman, Atteeq U , Schraders, Margit , Najmabadi, Hossein , Kremer, Hannie , Smith, Richard J H , Géléoc, Gwenaëlle S G , Dolan, David F , Raphael, Yehoash and Kohrman, David C

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-08, Vol.13 (8), p.e0201713-e0201713

Language

English

Formats

Articles

Publication information

Publisher

United States: Public Library of Science

Subjects

More information

Scope and Contents

Contents

Hearing and balance depend upon the precise morphogenesis and mechanosensory function of stereocilia, the specialized structures on the apical surface of sensory hair cells in the inner ear. Previous studies of Grxcr1 mutant mice indicated a critical role for this gene in control of stereocilia dimensions during development. In this study, we analy...

Alternative Titles

Full title

Grxcr2 is required for stereocilia morphogenesis in the cochlea

Authors, Artists and Contributors

Author / Creator

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Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2096655350

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2096655350

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0201713

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