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Expression of a recombinant, 4'-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase...

Expression of a recombinant, 4'-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2111726354

Expression of a recombinant, 4'-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase I in E. coli

About this item

Full title

Expression of a recombinant, 4'-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase I in E. coli

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-09, Vol.13 (9), p.e0204457-e0204457

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Fatty acid synthase 1 (FAS I) from Mycobacterium tuberculosis (Mtb) is an essential protein and a promising drug target. FAS I is a multi-functional, multi-domain protein that is organized as a large (1.9 MDa) homohexameric complex. Acyl intermediates produced during fatty acid elongation are attached covalently to an acyl carrier protein (ACP) dom...

Alternative Titles

Full title

Expression of a recombinant, 4'-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase I in E. coli

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2111726354

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2111726354

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0204457

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