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Age-specific changes in genome-wide methylation enrich for Foxa2 and estrogen receptor alpha binding...

Age-specific changes in genome-wide methylation enrich for Foxa2 and estrogen receptor alpha binding...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2112603312

Age-specific changes in genome-wide methylation enrich for Foxa2 and estrogen receptor alpha binding sites

About this item

Full title

Age-specific changes in genome-wide methylation enrich for Foxa2 and estrogen receptor alpha binding sites

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-09, Vol.13 (9), p.e0203147-e0203147

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The role of DNA methylation patterns in complex phenotypes remains unclear. To explore this question, we adapted our methods for rare variant analysis to characterize genome-wide murine DNA hybridization array to investigate methylation at CpG islands, shores, and regulatory elements. We have applied this platform to compare age and tissue- specifi...

Alternative Titles

Full title

Age-specific changes in genome-wide methylation enrich for Foxa2 and estrogen receptor alpha binding sites

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2112603312

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2112603312

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0203147

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