cGMP production of astatine-211-labeled anti-CD45 antibodies for use in allogeneic hematopoietic cel...
cGMP production of astatine-211-labeled anti-CD45 antibodies for use in allogeneic hematopoietic cell transplantation for treatment of advanced hematopoietic malignancies
About this item
Full title
Author / Creator
Univ. of Washington, Seattle, WA (United States) , Li, Yawen , Hamlin, Donald K , Chyan, Ming-Kuan , Wong, Roger , Dorman, Eric F , Emery, Robert C , Woodle, Douglas R , Manger, Ronald L , Nartea, Margaret , Kenoyer, Aimee L , Orozco, Johnnie J , Green, Damian J , Press, Oliver W , Storb, Rainer , Sandmaier, Brenda M and Wilbur, D Scott
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The objective of this study was to translate reaction conditions and quality control methods used for production of an astatine-211(211At)-labeled anti-CD45 monoclonal antibody (MAb) conjugate, 211At-BC8-B10, from the laboratory setting to cGMP production. Five separate materials were produced in the preparation of 211At-BC8-B10: (1) p-isothiocyana...
Alternative Titles
Full title
cGMP production of astatine-211-labeled anti-CD45 antibodies for use in allogeneic hematopoietic cell transplantation for treatment of advanced hematopoietic malignancies
Authors, Artists and Contributors
Author / Creator
Li, Yawen
Hamlin, Donald K
Chyan, Ming-Kuan
Wong, Roger
Dorman, Eric F
Emery, Robert C
Woodle, Douglas R
Manger, Ronald L
Nartea, Margaret
Kenoyer, Aimee L
Orozco, Johnnie J
Green, Damian J
Press, Oliver W
Storb, Rainer
Sandmaier, Brenda M
Wilbur, D Scott
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2122528367
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2122528367
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0205135
