Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice
Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice
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United States: Public Library of Science
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English
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United States: Public Library of Science
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NMDA receptors are important for cognition and are implicated in neuropsychiatric disorders. GluN1 knockdown (GluN1KD) mice have reduced NMDA receptor levels, striatal spine density deficits, and cognitive impairments. However, how NMDA depletion leads to these effects is unclear. Since Rho GTPases are known to regulate spine density and cognition,...
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Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice
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TN_cdi_plos_journals_2124452742
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2124452742
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0199341
