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Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ance...

Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ance...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2154252403

Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease

About this item

Full title

Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-12, Vol.13 (12), p.e0208828-e0208828

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Mitochondria play a significant role in human diseases. However, disease associations with mitochondrial DNA (mtDNA) SNPs have proven difficult to replicate. An analysis of eight schizophrenia-associated mtDNA SNPs, in 23,743 Danes without a psychiatric diagnosis and 2,538 schizophrenia patients, revealed marked inter-allelic differences in mitocho...

Alternative Titles

Full title

Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2154252403

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2154252403

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0208828

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