Bioprinted liver provides early insight into the role of Kupffer cells in TGF-β1 and methotrexate-in...
Bioprinted liver provides early insight into the role of Kupffer cells in TGF-β1 and methotrexate-induced fibrogenesis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Hepatic fibrosis develops from a series of complex interactions among resident and recruited cells making it a challenge to replicate using standard in vitro approaches. While studies have demonstrated the importance of macrophages in fibrogenesis, the role of Kupffer cells (KCs) in modulating the initial response remains elusive. Previous work dem...
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Bioprinted liver provides early insight into the role of Kupffer cells in TGF-β1 and methotrexate-induced fibrogenesis
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TN_cdi_plos_journals_2162764777
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2162764777
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0208958
