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In vitro anti-inflammatory effects of AZD8999, a novel bifunctional muscarinic acetylcholine recepto...

In vitro anti-inflammatory effects of AZD8999, a novel bifunctional muscarinic acetylcholine recepto...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2163347141

In vitro anti-inflammatory effects of AZD8999, a novel bifunctional muscarinic acetylcholine receptor antagonist /β2-adrenoceptor agonist (MABA) compound in neutrophils from COPD patients

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Full title

In vitro anti-inflammatory effects of AZD8999, a novel bifunctional muscarinic acetylcholine receptor antagonist /β2-adrenoceptor agonist (MABA) compound in neutrophils from COPD patients

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-01, Vol.14 (1), p.e0210188-e0210188

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Recent evidence indicates that AZD8999 (LAS190792), a novel muscarinic acetylcholine receptor antagonist and β2-adrenoceptor agonist (MABA) in development for chronic respiratory diseases, induces potent and sustained relaxant effects in human bronchi by adressing both muscarinic acetylcholine receptors and β2-adrenoceptor. However, the anti-inflam...

Alternative Titles

Full title

In vitro anti-inflammatory effects of AZD8999, a novel bifunctional muscarinic acetylcholine receptor antagonist /β2-adrenoceptor agonist (MABA) compound in neutrophils from COPD patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2163347141

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2163347141

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0210188

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