In vitro anti-inflammatory effects of AZD8999, a novel bifunctional muscarinic acetylcholine recepto...
In vitro anti-inflammatory effects of AZD8999, a novel bifunctional muscarinic acetylcholine receptor antagonist /β2-adrenoceptor agonist (MABA) compound in neutrophils from COPD patients
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Recent evidence indicates that AZD8999 (LAS190792), a novel muscarinic acetylcholine receptor antagonist and β2-adrenoceptor agonist (MABA) in development for chronic respiratory diseases, induces potent and sustained relaxant effects in human bronchi by adressing both muscarinic acetylcholine receptors and β2-adrenoceptor. However, the anti-inflam...
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In vitro anti-inflammatory effects of AZD8999, a novel bifunctional muscarinic acetylcholine receptor antagonist /β2-adrenoceptor agonist (MABA) compound in neutrophils from COPD patients
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TN_cdi_plos_journals_2163347141
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2163347141
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0210188