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Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthot...

Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthot...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2170922395

Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthotopic porcine limb vascularized composite allografts: A proof of concept study

About this item

Full title

Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthotopic porcine limb vascularized composite allografts: A proof of concept study

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-01, Vol.14 (1), p.e0210914-e0210914

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Currently, patients receiving vascularized composite allotransplantation (VCA) grafts must take long-term systemic immunosuppressive therapy to prevent immunologic rejection. The morbidity and mortality associated with these medications is the single greatest barrier to more patients being able to receive these life-enhancing transplants. In contra...

Alternative Titles

Full title

Graft-implanted, enzyme responsive, tacrolimus-eluting hydrogel enables long-term survival of orthotopic porcine limb vascularized composite allografts: A proof of concept study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2170922395

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2170922395

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0210914

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