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Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and indep...

Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and indep...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2181773406

Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer

About this item

Full title

Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-02, Vol.14 (2), p.e0211564-e0211564

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Ornithine decarboxylase (ODC) is the rate-limiting enzyme of polyamine synthesis. The two ODC antizyme inhibitors (AZIN1) and (AZIN2) are regulators of the catalytic activity of ODC. While AZIN1 is a regulator of cell proliferation, AZIN2 is involved in intracellular vesicle transport and secretion. There are no previous reports on the impact of AZ...

Alternative Titles

Full title

Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2181773406

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2181773406

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0211564

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