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Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pa...

Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2186921192

Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway

About this item

Full title

Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-02, Vol.14 (2), p.e0211244-e0211244

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Expulsion of parasitic gastrointestinal nematodes requires diverse effector mechanisms coordinated by a Th2-type response. The evolutionarily conserved JmjC protein; Myc Induced Nuclear Antigen (Mina) has been shown to repress IL4, a key Th2 cytokine, suggesting Mina may negatively regulate nematode expulsion. Here we report that expulsion of the p...

Alternative Titles

Full title

Myc-induced nuclear antigen constrains a latent intestinal epithelial cell-intrinsic anthelmintic pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2186921192

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2186921192

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0211244

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