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Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insuli...

Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insuli...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2199464985

Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation

About this item

Full title

Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-03, Vol.14 (3), p.e0214122-e0214122

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Branched chain amino acids (BCAA) are essential elements of the human diet, which display increased plasma levels in obesity and regained particular interest as potential biomarkers for development of diabetes. To define determinants of insulin resistance (IR) we investigated 73 genes involved in BCAA metabolism or regulation by fine-scale haplotyp...

Alternative Titles

Full title

Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2199464985

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2199464985

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0214122

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