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Crosstalks of the PTPIP51 interactome revealed in Her2 amplified breast cancer cells by the novel sm...

Crosstalks of the PTPIP51 interactome revealed in Her2 amplified breast cancer cells by the novel sm...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2223020319

Crosstalks of the PTPIP51 interactome revealed in Her2 amplified breast cancer cells by the novel small molecule LDC3/Dynarrestin

About this item

Full title

Crosstalks of the PTPIP51 interactome revealed in Her2 amplified breast cancer cells by the novel small molecule LDC3/Dynarrestin

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-05, Vol.14 (5), p.e0216642

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

LDC3/Dynarrestin, an aminothiazole derivative, is a recently developed small molecule, which binds protein tyrosine phosphatase interacting protein 51 (PTPIP51). PTPIP51 interacts with various proteins regulating different signaling pathways leading to proliferation and migration. Her2 positive breast cancer cells (SKBR3) express high levels of PTP...

Alternative Titles

Full title

Crosstalks of the PTPIP51 interactome revealed in Her2 amplified breast cancer cells by the novel small molecule LDC3/Dynarrestin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2223020319

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2223020319

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0216642

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