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Metabolic, mitochondrial, renal and hepatic safety of enfuvirtide and raltegravir antiretroviral adm...

Metabolic, mitochondrial, renal and hepatic safety of enfuvirtide and raltegravir antiretroviral adm...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2229634040

Metabolic, mitochondrial, renal and hepatic safety of enfuvirtide and raltegravir antiretroviral administration: Randomized crossover clinical trial in healthy volunteers

About this item

Full title

Metabolic, mitochondrial, renal and hepatic safety of enfuvirtide and raltegravir antiretroviral administration: Randomized crossover clinical trial in healthy volunteers

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-05, Vol.14 (5), p.e0216712

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Classical antiretroviral agents may acutely impact on metabolic, mitochondrial, renal and hepatic function in HIV-infected and uninfected persons. Fusion and integrase inhibitors are supposed to be safer, but have been scarcely investigated. To avoid any interference with HIV or other antiretrovirals, we assessed markers of these toxicities in heal...

Alternative Titles

Full title

Metabolic, mitochondrial, renal and hepatic safety of enfuvirtide and raltegravir antiretroviral administration: Randomized crossover clinical trial in healthy volunteers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2229634040

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2229634040

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0216712

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