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Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irra...

Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irra...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2239658153

Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irradiation through apoptosis induction

About this item

Full title

Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irradiation through apoptosis induction

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-06, Vol.14 (6), p.e0218049-e0218049

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Recent studies have highlighted the implications of genetic variations in the relative biological effectiveness (RBE) of proton beam irradiation over conventional X-ray irradiation. Proton beam radiotherapy is a reasonable radiotherapy option for hepatocellular carcinoma (HCC), but the impact of genetic difference on the HCC RBE remains unknown. He...

Alternative Titles

Full title

Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irradiation through apoptosis induction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2239658153

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2239658153

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0218049

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