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Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer...

Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2240301274

Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer genome analysis

About this item

Full title

Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer genome analysis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-06, Vol.14 (6), p.e0217724-e0217724

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In addition to conventional cytology, liquid-based cytology (LBC) is also used for immunocytochemistry and gene analysis. However, an appropriate method to obtain high quality DNA for next-generation sequencing (NGS) using LBC specimens remains controversial. We determined the optimal conditions for fixation with an alcohol-based fixative for LBC a...

Alternative Titles

Full title

Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer genome analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2240301274

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2240301274

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0217724

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