Disease-associated mutations in human TUBB3 disturb netrin repulsive signaling
Disease-associated mutations in human TUBB3 disturb netrin repulsive signaling
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Missense mutations in the human TUBB3 gene cause a variety of neurological disorders associated with defects in axon guidance and neuronal migration, but the underlying molecular mechanisms are not well understood. Recent studies have shown that direct coupling of dynamic TUBB3 in microtubules with netrin receptors is required for netrin-1-mediated...
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Disease-associated mutations in human TUBB3 disturb netrin repulsive signaling
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TN_cdi_plos_journals_2244644219
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2244644219
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0218811
