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Tumor M2-PK: A novel urine marker of bladder cancer

Tumor M2-PK: A novel urine marker of bladder cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2248369311

Tumor M2-PK: A novel urine marker of bladder cancer

About this item

Full title

Tumor M2-PK: A novel urine marker of bladder cancer

Publisher

United States: Public Library of Science

Journal title

PloS one, 2019-06, Vol.14 (6), p.e0218737-e0218737

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Bladder cancer is a "Warburg-like" tumor characterized by a reliance on aerobic glycolysis and expression of pyruvate kinase M2 (PKM2). PKM2 oscillates between an active tetramer and an inactive dimer. We aim to further characterize PKM2, in particular PKM2 dimer, as a urinary biomarker of bladder cancer and a potential target for treatment.
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Alternative Titles

Full title

Tumor M2-PK: A novel urine marker of bladder cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2248369311

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2248369311

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0218737

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