Tumor M2-PK: A novel urine marker of bladder cancer
Tumor M2-PK: A novel urine marker of bladder cancer
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Bladder cancer is a "Warburg-like" tumor characterized by a reliance on aerobic glycolysis and expression of pyruvate kinase M2 (PKM2). PKM2 oscillates between an active tetramer and an inactive dimer. We aim to further characterize PKM2, in particular PKM2 dimer, as a urinary biomarker of bladder cancer and a potential target for treatment.
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Full title
Tumor M2-PK: A novel urine marker of bladder cancer
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TN_cdi_plos_journals_2248369311
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2248369311
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0218737