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Phosphoglucomutase 1 inhibits hepatocellular carcinoma progression by regulating glucose trafficking

Phosphoglucomutase 1 inhibits hepatocellular carcinoma progression by regulating glucose trafficking

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2249945500

Phosphoglucomutase 1 inhibits hepatocellular carcinoma progression by regulating glucose trafficking

About this item

Full title

Phosphoglucomutase 1 inhibits hepatocellular carcinoma progression by regulating glucose trafficking

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2018-10, Vol.16 (10), p.e2006483-e2006483

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Glycogen metabolism commonly altered in cancer is just beginning to be understood. Phosphoglucomutase 1 (PGM1), the first enzyme in glycogenesis that catalyzes the reversible conversion between glucose 1-phosphate (G-1-P) and glucose 6-phosphate (G-6-P), participates in both the breakdown and synthesis of glycogen. Here, we show that PGM1 is down-r...

Alternative Titles

Full title

Phosphoglucomutase 1 inhibits hepatocellular carcinoma progression by regulating glucose trafficking

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2249945500

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2249945500

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.2006483

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