Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery b...
Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic
About this item
Full title
Author / Creator
Boehme, Jason , Le Moan, Natacha , Kameny, Rebecca J , Loucks, Alexandra , Johengen, Michael J , Lesneski, Amy L , Gong, Wenhui , Goudy, Brian D. , Davis, Tina , Tanaka, Kevin , Davis, Andrew , He, Youping , Long-Boyle, Janel , Ivaturi, Vijay , Gobburu, Jogarao V S , Winger, Jonathan A , Cary, Stephen P , Datar, Sanjeev A , Fineman, Jeffrey R , Krtolica, Ana and Maltepe, Emin
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The heart exhibits the highest basal oxygen (O2) consumption per tissue mass of any organ in the body and is uniquely dependent on aerobic metabolism to sustain contractile function. During acute hypoxic states, the body responds with a compensatory increase in cardiac output that further increases myocardial O2 demand, predisposing the heart to is...
Alternative Titles
Full title
Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic
Authors, Artists and Contributors
Author / Creator
Le Moan, Natacha
Kameny, Rebecca J
Loucks, Alexandra
Johengen, Michael J
Lesneski, Amy L
Gong, Wenhui
Goudy, Brian D.
Davis, Tina
Tanaka, Kevin
Davis, Andrew
He, Youping
Long-Boyle, Janel
Ivaturi, Vijay
Gobburu, Jogarao V S
Winger, Jonathan A
Cary, Stephen P
Datar, Sanjeev A
Fineman, Jeffrey R
Krtolica, Ana
Maltepe, Emin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2249952832
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2249952832
Other Identifiers
ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.2005924
