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Alternative (backdoor) androgen production and masculinization in the human fetus

Alternative (backdoor) androgen production and masculinization in the human fetus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2249959958

Alternative (backdoor) androgen production and masculinization in the human fetus

About this item

Full title

Alternative (backdoor) androgen production and masculinization in the human fetus

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2019-02, Vol.17 (2), p.e3000002-e3000002

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Masculinization of the external genitalia in humans is dependent on formation of 5α-dihydrotestosterone (DHT) through both the canonical androgenic pathway and an alternative (backdoor) pathway. The fetal testes are essential for canonical androgen production, but little is known about the synthesis of backdoor androgens, despite their known critic...

Alternative Titles

Full title

Alternative (backdoor) androgen production and masculinization in the human fetus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2249959958

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2249959958

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3000002