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Exploring the impact of inoculum dose on host immunity and morbidity to inform model-based vaccine d...

Exploring the impact of inoculum dose on host immunity and morbidity to inform model-based vaccine d...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2250631719

Exploring the impact of inoculum dose on host immunity and morbidity to inform model-based vaccine design

About this item

Full title

Exploring the impact of inoculum dose on host immunity and morbidity to inform model-based vaccine design

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2018-10, Vol.14 (10), p.e1006505-e1006505

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Vaccination is an effective method to protect against infectious diseases. An important consideration in any vaccine formulation is the inoculum dose, i.e., amount of antigen or live attenuated pathogen that is used. Higher levels generally lead to better stimulation of the immune response but might cause more severe side effects and allow for less...

Alternative Titles

Full title

Exploring the impact of inoculum dose on host immunity and morbidity to inform model-based vaccine design

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2250631719

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2250631719

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1006505

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