Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas canc...
Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer
About this item
Full title
Author / Creator
Gendoo, Deena M. A. , Denroche, Robert E. , Zhang, Amy , Radulovich, Nikolina , Jang, Gun Ho , Lemire, Mathieu , Fischer, Sandra , Chadwick, Dianne , Lungu, Ilinca M. , Ibrahimov, Emin , Cao, Ping-Jiang , Stein, Lincoln D. , Wilson, Julie M. , Bartlett, John M. S. , Tsao, Ming-Sound , Dhani, Neesha , Hedley, David , Gallinger, Steven and Haibe-Kains, Benjamin
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Pancreatic ductal adenocarcinoma (PDAC) has the worst prognosis among solid malignancies and improved therapeutic strategies are needed to improve outcomes. Patient-derived xenografts (PDX) and patient-derived organoids (PDO) serve as promising tools to identify new drugs with therapeutic potential in PDAC. For these preclinical disease models to b...
Alternative Titles
Full title
Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer
Authors, Artists and Contributors
Author / Creator
Denroche, Robert E.
Zhang, Amy
Radulovich, Nikolina
Jang, Gun Ho
Lemire, Mathieu
Fischer, Sandra
Chadwick, Dianne
Lungu, Ilinca M.
Ibrahimov, Emin
Cao, Ping-Jiang
Stein, Lincoln D.
Wilson, Julie M.
Bartlett, John M. S.
Tsao, Ming-Sound
Dhani, Neesha
Hedley, David
Gallinger, Steven
Haibe-Kains, Benjamin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2250637396
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2250637396
Other Identifiers
ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1006596
