Prediction of VRC01 neutralization sensitivity by HIV-1 gp160 sequence features
Prediction of VRC01 neutralization sensitivity by HIV-1 gp160 sequence features
About this item
Full title
Author / Creator
Magaret, Craig A. , Benkeser, David C. , Williamson, Brian D. , Borate, Bhavesh R. , Carpp, Lindsay N. , Georgiev, Ivelin S. , Setliff, Ian , Dingens, Adam S. , Simon, Noah , Carone, Marco , Simpkins, Christopher , Montefiori, David , Alter, Galit , Yu, Wen-Han , Juraska, Michal , Edlefsen, Paul T. , Karuna, Shelly , Mgodi, Nyaradzo M. , Edugupanti, Srilatha and Gilbert, Peter B.
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The broadly neutralizing antibody (bnAb) VRC01 is being evaluated for its efficacy to prevent HIV-1 infection in the Antibody Mediated Prevention (AMP) trials. A secondary objective of AMP utilizes sieve analysis to investigate how VRC01 prevention efficacy (PE) varies with HIV-1 envelope (Env) amino acid (AA) sequence features. An exhaustive analy...
Alternative Titles
Full title
Prediction of VRC01 neutralization sensitivity by HIV-1 gp160 sequence features
Authors, Artists and Contributors
Author / Creator
Benkeser, David C.
Williamson, Brian D.
Borate, Bhavesh R.
Carpp, Lindsay N.
Georgiev, Ivelin S.
Setliff, Ian
Dingens, Adam S.
Simon, Noah
Carone, Marco
Simpkins, Christopher
Montefiori, David
Alter, Galit
Yu, Wen-Han
Juraska, Michal
Edlefsen, Paul T.
Karuna, Shelly
Mgodi, Nyaradzo M.
Edugupanti, Srilatha
Gilbert, Peter B.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2250643537
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2250643537
Other Identifiers
ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1006952
