AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and s...
AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The human 1q21.1 deletion of ten genes is associated with increased risk of schizophrenia. This deletion involves the β-subunit of the AMP-activated protein kinase (AMPK) complex, a key energy sensor in the cell. Although neurons have a high demand for energy and low capacity to store nutrients, the role of AMPK in neuronal physiology is poorly def...
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Full title
AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance
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TN_cdi_plos_journals_2251023041
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251023041
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1007623
