Amino acid residues in five separate HLA genes can explain most of the known associations between th...
Amino acid residues in five separate HLA genes can explain most of the known associations between the MHC and primary biliary cholangitis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Primary Biliary Cholangitis (PBC) is a chronic autoimmune liver disease characterised by progressive destruction of intrahepatic bile ducts. The strongest genetic association is with HLA-DQA1*04:01, but at least three additional independent HLA haplotypes contribute to susceptibility. We used dense single nucleotide polymorphism (SNP) data in 2861...
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Full title
Amino acid residues in five separate HLA genes can explain most of the known associations between the MHC and primary biliary cholangitis
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TN_cdi_plos_journals_2251023359
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251023359
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1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1007833
