The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombi...
The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Breast cancer susceptibility gene 1 (BRCA1) and binding partner BRCA1-associated RING domain protein 1 (BARD1) form an essential E3 ubiquitin ligase important for DNA damage repair and homologous recombination. The Caenorhabditis elegans orthologs, BRC-1 and BRD-1, also function in DNA damage repair, homologous recombination, as well as in meiosis....
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The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans
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TN_cdi_plos_journals_2251023999
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251023999
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1553-7404,1553-7390
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1553-7404
DOI
10.1371/journal.pgen.1007701