Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease
Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease
About this item
Full title
Author / Creator
Runtsch, Marah C. , Nelson, Morgan C. , Lee, Soh-Hyun , Voth, Warren , Alexander, Margaret , Hu, Ruozhen , Wallace, Jared , Petersen, Charisse , Panic, Vanja , Villanueva, Claudio J. , Evason, Kimberley J. , Bauer, Kaylyn M. , Mosbruger, Timothy , Boudina, Sihem , Bronner, Mary , Round, June L. , Drummond, Micah J. and O’Connell, Ryan M.
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Identifying regulatory mechanisms that influence inflammation in metabolic tissues is critical for developing novel metabolic disease treatments. Here, we investigated the role of microRNA-146a (miR-146a) during diet-induced obesity in mice. miR-146a is reduced in obese and type 2 diabetic patients and our results reveal that miR-146a-/- mice fed a...
Alternative Titles
Full title
Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease
Authors, Artists and Contributors
Author / Creator
Nelson, Morgan C.
Lee, Soh-Hyun
Voth, Warren
Alexander, Margaret
Hu, Ruozhen
Wallace, Jared
Petersen, Charisse
Panic, Vanja
Villanueva, Claudio J.
Evason, Kimberley J.
Bauer, Kaylyn M.
Mosbruger, Timothy
Boudina, Sihem
Bronner, Mary
Round, June L.
Drummond, Micah J.
O’Connell, Ryan M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2251042197
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251042197
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1007970
