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Dual functions for the ssDNA-binding protein RPA in meiotic recombination

Dual functions for the ssDNA-binding protein RPA in meiotic recombination

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251043156

Dual functions for the ssDNA-binding protein RPA in meiotic recombination

About this item

Full title

Dual functions for the ssDNA-binding protein RPA in meiotic recombination

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2019-02, Vol.15 (2), p.e1007952-e1007952

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Meiotic recombination permits exchange of genetic material between homologous chromosomes. The replication protein A (RPA) complex, the predominant ssDNA-binding complex, is required for nearly all aspects of DNA metabolism, but its role in mammalian meiotic recombination remains unknown due to the embryonic lethality of RPA mutant mice. RPA is a h...

Alternative Titles

Full title

Dual functions for the ssDNA-binding protein RPA in meiotic recombination

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2251043156

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251043156

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1007952

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